Job Summary : Amgen's Digital Integration and Predictive Technologies organization is a global process development function that develops and deploys state of the art advanced computational technologies in: 1) data capture, integration and management, 2) empirical and first principles modeling towards improved process understanding and robustness, and 3) monitoring, prediction and optimization of manufacturing. We are seeking a Senior Engineer to develop, apply and deploy rigorous mathematical models of process technologies with the goal to increase the efficiency of drug development and manufacturing processes. The candidate will apply biophysicochemical, multi-physics and computational fluid dynamics (CFD) modeling to produce and maintain first-principles and mechanistic models addressing a wide variety of challenging problems across many functions including: drug substance, drug product and drug delivery devices. Responsibilities will include identifying key product/unit/systems properties/phenomena, formulating the fundamental equations describing these, examining modeling simplification and assumptions, implementing models in commercial and proprietary software and deploying these models to internal users via an enterprise modeling infrastructure. The Senior Engineer will collaborate heavily with internal stakeholders, as well as document and communicate the underlying technical basis of the models for the benefit of and use by engineers and scientists responsible for delivering processes and devices to operations. Basic Qualifications: Doctorate degree OR Master's degree & 3 years of related engineering experience OR Bachelor's degree & 6 years of related engineering experience OR Associate's degree & 8 years of related engineering experience OR High school diploma / GED & 10 years of related engineering experience Preferred Qualifications Ph.D. in Chemical or Mechanical Engineering or related field. Experience in mathematical and computational (in-silico) modeling, and experience in process development is highly desired. Modeling of fluid mechanic processes and/or mechanical devices. Modeling of chemical reaction or combustion systems. Understanding of bio-pharmaceutical processes, unit operations and drug delivery devices. Basic programming skills Good interdisciplinary project management skills. Ability to independently uncover and resolve issues associated with the development and implementation of scientific and engineering projects. Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology. Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential. Join Us If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen. Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. . Associated topics: assembly, automotive, boiler, machine, mechanical, msme, proe, rotordynamic, solidworks, turbine
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