Process Research and Development (PRD) develops processes and prepares active pharmaceutical ingredient (API) to enable clinical trials, toxicology studies and drug product development for AbbVie's pre-clinical and clinical drug pipeline. Researchers in AbbVie's R&D work in multi-functional teams to develop scalable processes and supply API for safety testing, clinical trials and formulation development.
To achieve this goal, Process R&D researchers use a variety of automation techniques to expedite process development which include:
High throughput experimentation for screening and process parameter mapping
Medium throughput experimentation and automated laboratory reactors to expedite process optimization and enhance process understanding
Custom automation to maximize opportunities for greater experimental efficiency and to enable development of continuous and flow processes.
The successful candidate will play a key role in furthering the automation capabilities within Process R&D. Key responsibilities include:
Develop and maintain instrument drivers for pumps, chillers, stirrer motors, Process Analytical Technologies (PAT) and related laboratory process equipment
Integrate laboratory equipment, PAT, and data analytics to establish custom automated API process development platforms with attention to understanding business and user requirements
Design laboratory scale automated systems and lead the implementation of continuous flow processing platforms
Implement coherent data management systems across laboratories
Develop a network and establish working relations with in-house automation groups, equipment vendors, and third party hardware/software development companies
Define best practices, training, and develop support systems to maintain automated process development platforms
Actively seek opportunities, collaborate, and demonstrate impact from automated process development platforms on pipeline projects
*Level will be based on education and years of experience
PhD in Chemistry/Chemical, Mechanical, Electrical or Computer Engineering with relevant experience in automation required. Industrial experience is preferred.
Experience with automation, engineering design and technical expertise in the areas of integration, robotics, equipment communications protocols, software and electro-mechanical solutions.
Demonstrated ability in programming and debugging automated systems using languages such as LabVIEW, Python, C, C#, or similar. Familiarity with Linux OS on embedded systems a plus.
Practical capability to setup and operate laboratory process equipment.
Key Leadership Competencies:
Builds strong relationships with peers and cross functionally with partners to enable higher performance.
Learns fast, grasps the \"essence\" and can change course quickly where indicated.
Raises the bar and is never satisfied with the status quo.
Creates a learning environment, open to suggestions and experimentation for improvement.
Embraces the ideas of others, nurtures innovation and manages innovation to reality.
Strong interpersonal and communication skills with demonstrated ability to work within a team environment.